what drugs to avoid if allergic to penicillin?10 marca 2023
Home | About | Contact | Copyright | Privacy | Cookie Policy | Terms & Conditions | Sitemap. Begin by trying to establish if the harm was caused by medication, or something else. The American College of Allergy, Asthma and Immunology lists the following antibiotics as ones to avoid if you have a penicillin allergy: Amoxicillin Ampicillin Dicloxacillin Nafcillin Oxacillin Penicillin G Penicillin V Piperacillin Ticarcillin Cefaclor Cefadroxil Cefazolin Cefdinir Cefotetan Cefprozil Cefuroxime Cephalexin (Keflex) However, molecular traces of these proteins may be present in fish oil, and there is a chance you could have an allergic reaction to fish oil if you are allergic to shellfish. Tingling or itching in your mouth. Tetracyclines (e.g. https://www.merckmanuals.com/professional/immunology-allergic-disorders/allergic,-autoimmune,-and-other-hypersensitivity-disorders/anaphylaxis?query=anaphylaxis. Only a small percentage of people (around 10%) with a penicillin allergy will react to a cephalosporin. This leads to misdiagnosis and use of inappropriate antibiotics for treating patients condition that are less effective. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. You may eat or drink these products with your meals, but do not use them alone when taking ciprofloxacin. Who Is The Father Of Jodie Fosters Baby? Increased exposure to penicillin, because of high doses, repetitive use or prolonged use; Certain illnesses commonly associated with allergic drug reactions, such as infection with HIV or the Epstein-Barr virus; Prevention. Stopping the bacterial DNA replications means the bacterial cells will no longer be able to multiply or divide now, because DNA replication is necessary for cell division and bacterial growth. A scheme for assessing a patient who describes a drug allergy, based on our experience, is set out in figure 1. By continuing to use the service, you agree to our use of cookies. Penicillin allergy occurs when the bodys immune system shows overreacted response against penicillin antibiotics. Which Is More Stable Thiophene Or Pyridine? But how it is possible? asthma or wheezing. In particular, this supplement is used for osteoarthritis, according to Medline Plus. Besides penicillins, other beta lactams are given as such: Drugs belonging to this class are the potent inhibitors of bacterial protein synthesis. 1. For emergency purposes, it is wise to wear a bracelet that states your allergies. Before taking this medication, tell your doctor if you are allergic to any drugs (especially penicillin). As a . Cephalosporins. Shenoy ES, et al. Signs and symptoms of anaphylaxis include: Less-common penicillin allergy reactions occur days or weeks after exposure to the drug and may persist for some time after you stop taking it. When these crucial enzymes are inhibited through drug action, DNA replication stops. Other times, the side effects may be severe enough that a doctor may choose to stop the medicine all together. Is It Safe to Take a Fish Oil Capsule With Milk? These vary but may include: Asthma -like symptoms, such as wheezing and trouble breathing. An allergy to penicillin-type drugs is the only one that can be definitively diagnosed through a skin test. Examples are resistant staphylococci and gram negative bacteria. Amoxicillin is a penicillin-type antibiotic and Cipro is a fluoroquinolone antibiotic. Having a true allergy to penicillin is serious. Keflex is a cephalosporin antibiotic and amoxicillin is a penicillin-type antibiotic. However, Medline Plus indicates shellfish allergies are usually based on the meat of shellfish rather than the shell, and many people with shellfish allergies can take glucosamine sulfate without adverse reactions. Penicillin vk is used to treat the following conditions: Bacterial Infection. Antibiotics in the penicillin class are one of the most commonly prescribed antibiotics and include many individual medications, such as penicillin G, amoxicillin, nafcillin, oxacillin, dicloxacillin, flucloxacillin, ampicillin, carbenicillin, ticarcillin, and piperacillin. Allergic reactions to shellfish or peanuts can be serious or even life-threatening. Since the discovery and development of penicillin G, the first type of penicillin, several other types have been developed, including penicillin V, procaine penicillin and benzathine penicillin. Some of the common signs and symptoms of penicillin allergy are: Anaphylaxis is described as an allergic reaction that involves all the organs of the body and proves to be a fatal condition. They may be prescribed to treat urinary tract infections (UTIs), bronchitis, eye infections, bacterial meningitis, pneumonia, ear infections, severe burns, travelers diarrhea, and other conditions. Apart from coverage against gram positive organism, these wide spectrum drugs are also active against gram negative rods too including Listeria monocytgenes, Escherichia coli, Proteus mirabilis, Haemophilus influenzae, Klebsiella, pseudomonas and Enterobacter species. Patients who have had an anaphylactic reaction to penicillin are often prescribed an emergency self-injecting epinephrine. information is beneficial, we may combine your email and website usage information with When you get a new prescription, it is a good idea to read over the information packet and discuss questions with a doctor or pharmacist so you can understand its potential for causing a drug allergy, side effects or other types of adverse drug reactions. There are a number of cephalosporin medications available, including cephalexin (brand name: Keflex), cefaclor (brand name: Ceclor), cefuroxime (brand name: Ceftin), cefadroxil (brand name: Duricef), cefprozil (brand name: Cefzil), ceftibuten (brand name: Cedax), cefdinir (brand name: Omnicef), cefpodoxime, and cefixime (brand name: Suprax). Both drug are used to treat bacterial infections such as urinary tract infections, bronchitis and other lung infections. Anyone who is allergic to one type of penicillin should be considered allergic to all penicillin and should avoid the entire medication group. How does Augmentin work? Some bacteria develop efflux pumps in their cell wall. What dose of co-trimoxazole is used in a patient with a UTI? Other antibiotics, particularly those with chemical properties similar to penicillin, also can result in allergic reactions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. However, there are other medications you may be able to take. ciprofloxacin), macrolides (e.g. Accessed Oct. 24, 2019. Had sudden dizziness, weakness or loss of consciousness. Why should I be evaluated for a penicillin allergy? Which antibiotic is best for throat infection? Last updated on Nov 10, 2021. Here are the four generations of fluoroquinolones: Bacteria need to synthesize folic acids for DNA replication and synthesis. Accessed Oct. 22, 2019. A single copy of these materials may be reprinted for noncommercial personal use only. Prometrium is also prescribed to people whose periods stop before menopause. Steps you can take to protect yourself include the following: Mayo Clinic does not endorse companies or products. information submitted for this request. What kind of bacteria does Zithromax treat? According toinformation published by the University of Bristol, penicillin works by destroying the cell walls of bacteria and deactivating the enzyme responsible for the growth of the cell walls. It's important to understand and discuss what is an allergic reaction, what is a typical side effect and what you can tolerate in taking a medication. Can I take doxycycline if I am allergic to penicillin? Not every reaction to a medication is a drug allergy. Ancef (cefazolin) is a cephalosporin, which is a class of antibiotics that are like cousins to penicillin. Most hospitals or clinics have access to an allergist / immunologist who can help facilitate this. If you've had an allergic reaction to one type of penicillin, you may be but are not necessarily allergic to other types of penicillin or to some cephalosporins. Drug rash with eosinophilia and systemic syndrome (DRESS). 7 possible causes. This is why it is crucial for patients to let their doctors and pharmacists know of any medications (including over-the counter), vitamins and supplements they are taking. Sulfonamides, or sulfa drugs, are a group of medicines used to treat bacterial infections. Therefore, other antibiotics can be used safely in patients with history of penicillin allergy. Is penicillin allergy genetic? The short answer is yes, but you may never have been allergic to begin with. More than 90 percent of people who believe they are allergic to penicillin really aren't. privacy practices. Theyre actually in the same family of antibiotics, called the penicillin family. Your email address will not be published. Norepinephrine vs epinephrine: what's the difference? This patient centered episode discusses why 90% of those who report a penicillin allergy are not truly allergic. Research is mixed on whether there is an association between allergies to antibiotic sulfa drugs and nonantibiotic sulfa drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. But penicillin inhibits the formation of cell wall in bacteria that makes them vulnerable to bodys harsh environment. Penicillin allergy is the most common drug allergy and is reported in up to 15 percent of hospitalized patients [].A frequent clinical question is whether these patients can safely receive the structurally related cephalosporins or carbapenems (monobactams [ie, aztreonam] are not cross-reactive with penicillins and can be safely given to penicillin-allergic patients). Enfermedades de Inmunodeficiencia Primaria, AAAAI Diversity Equity and Inclusion Statement. of signs you need emergency medical attention or call 911. Cephalosporins are used for similar reasons. Sustanon is typically injected once every three weeks at a 1 ml. However, if you have had specialized testing in the past that has indicated you are allergic to penicillin such as a skin test or oral challenge and have an infection that requires immediate treatment, the safest approach is to perform a procedure called desensitization. Examples of a medication allergy may include anaphylaxis from an antibiotic, angioedema (swelling in layers of the skin) from an ACE inhibitor or a rash from aspirin. The first patient was successfully treated for streptococcal septicemia in the United States in 1942. In cases of a positive penicillin test, either the skin prick or intradermal test will produce a red, raised bump, signifying the presence of an allergy to the medication. Using other drugscalled broad-spectrum antibioticsinstead of penicillin can be more expensive and less effective. What is the best way to reduce swelling in your face? Sulfadiazine silver (Silvadene), a cream to prevent and treat burn infections. Penicillin allergy signs and symptoms may include: Official Answer. Dont limit your treatment options find out for sure whether youre allergic. Available for Android and iOS devices. Fusospirochetosis, Trench Mouth. There are also many broad-spectrum antibiotics that can be used in place of penicillin. An allergist / immunologist can perform this testing, and if it is negative, there is a very high chance that the allergy is no longer present. Epinephrine results in instantaneous relief and counters the symptoms of an allergy attack. If it was an ADR, consider whether the . Accessed Oct. 22, 2019. blistering, peeling, or loosening of the skin. clarithromycin), aminoglycosides (e.g. In the meantime, it is best to stay away from antibiotics that belong to the penicillin family and cephalosporin family, a type of drug that is closely related to penicillin. Allergic to Penicillin? Allergy to Penicillin Drugs Mold Allergies and Food Allergies Peanut oil is present in Sustanon, so you should avoid this medicine if you have an allergy to peanuts. If you have a true penicillin allergy, you should not take any antibiotics in the penicillin family. Many people experience constipation with narcotic medications. Sulfamethoxazole / trimethoprim (Bactrim, Sulfatrim), a sulfa combination drug that can be taken in liquid or pill form for many types of infections. In addition to penicillins, other beta-lactams more commonly associated with allergic reactions are a group called cephalosporins. Evaluation and management of penicillin allergy. While penicillin still remains the most widely used antibiotic in the world, Dr. Barbara Baxter, a doctor in Dallas, notes that there is a percentage of the population that must steer clear of this drug. However, the allergist / immunologist will discuss the particular protocol they plan to use for skin testing with you at your visit. A penicillin allergy is a reaction by your immune system to the antibiotic drug penicillin. Sulfacetamide (BLEPH-10), drops for eye infections. https://acaai.org/allergies/types/drug-allergies. Centers for Disease Control and Prevention, https://www.cdc.gov/antibiotic-use/clinicians/Penicillin-Allergy.html, https://www.ncbi.nlm.nih.gov/books/NBK482250/, https://www.aaaai.org/Tools-for-the-Public/Conditions-Library/Allergies/Penicillin-Allergy-FAQ. Allergic person may not complain of allergic symptoms on first time intake of penicillin antibiotic because the level of antibodies produced at first exposure are not enough to launch a full fledge allergic reaction. These infections are both serious and hard to treat. Can you have the Pfizer vaccine if allergic to penicillin? Allegra vs Zyrtec: What's the difference? Has anyone had an anaphylactic reaction to the J&J Covid vaccine? Thus, all above mechanism are responsible for making bacteria resistant to penicillin action. Penicillin is prescribed for treating various bacterial infections. Chemicals released by this activity cause the signs and symptoms associated with an allergic reaction. Penicillins belong to a class of drug called beta lactams because they contain a special beta lactam ring in their structure that is considered to be responsible for its anti microbial activity. What Was The Ping Pong Diplomacy Quizlet? It's not an antibiotic, but it should also be avoided in people allergic to sulfonamide antibiotics. This information packed episode is useful for patients, the general public and medical professionals. Symptoms can begin within moments of ingesting a medication or up to several hours later. These drugs are also more likely to cause antibiotic resistance and result in an infection that is very hard to treat. Previous exposure to penicillin may not be obvious. Certain vaccines including the flu vaccine contain small amounts of egg. These include:If you have a penicillin allergy, the simplest prevention is to avoid the drug. Dried fruits (excluding dark raisins and prunes), Grape juices (white, white sparkling, pink sparkling, red sparkling). Dont wait until youre in a medical emergency. Some patients who experience a reaction after their first intake of penicillin do not go on to develop a lifelong allergy to it, even if that reaction were as drastic as anaphylaxis. Swelling of the lips, face or eyes. Milk is discarded if it has too much of those drugs in it. The absorption half-life of the drug was 0.4-0.6 day in the egg-white and 0.93-1.08 day in the egg-yolk. penicillin, ampicillin, amoxicillin, amoxicillin-clavulanate, methicillin) that are given by mouth or injection for the treatment of many bacterial infections. Anaphylaxis. Severe reactions include anaphylaxis, a life-threatening condition that affects multiple body systems. Review/update the What is the Best Way to Clean a BBQ Grill? Which Is More Stable Thiophene Or Pyridine? Testing should only be conducted by an allergist trained to recognize and treat potential allergic reactions. Two trial participants suffered severe allergic reactions shortly after getting Johnson & Johnsons Covid-19 vaccine, a J&J scientist told an FDA panel on Friday. 2023 American Academy of Allergy, Asthma & Immunology. Non-immediate symptoms can include: Red patches (macules) or papules (bumps) on the skin. gentamicin) and glycopeptides (e.g. When this happens, the microorganism is rendered vulnerable to osmotic pressure and thus, bursts and dies. Antibiotic allergies are an immunologically mediated response to a pharmaceutical in a sensitized person and are mediated by IgE, IgG, or T lymphocytes. There are very few cases in which allergy testing or desensitization for penicillin is dangerous. Amoxicillin and penicillin are two of many antibiotics on the market today. Peanuts and other nuts Peanuts contain aflatoxin, which is considered a human carcinogen. Based on these factors, you and your doctor can decide whether you should have testing for a penicillin allergy. What will happen during my visit with the allergist / immunologist? Prometrium is a proprietary brand of progesterone capsule used after menopause in combination with estrogen. Penicillin is prescribed for treating various bacterial infections. Penicillin allergy is more likely to occur in those people suffering from allergy conditions like urticaria and asthma. Depending on the type of penicillin, common side effects may include mild nausea or diarrhea, headache, or vaginal itching. Zyrtec vs Claritin: Which is more effective for allergies? J&J says two trial participants had severe allergic reactions after getting Covid vaccine. No interactions were found between ibuprofen and Penicillin VK. You may opt-out of email communications at any time by clicking on Fish oil does not contain protein from shellfish flesh, which typically triggers the shellfish allergic reaction. It is also good practice to keep a list of medications and their doses in a wallet and update all healthcare providers when there are any changes. Glucosamine sulfate is a dietary supplement used as a complementary therapy for arthritis. Severe reactions include anaphylaxis, a life-threatening condition that affects multiple body systems. Can You Outgrow a Penicillin Allergy? Journal of the American Medical Association. Save my name, email, and website in this browser for the next time I comment. This content does not have an Arabic version. An allergic reaction to penicillin in childhood does not automatically predict a reaction as an adult. If you don't have a reaction to the oral challenge or the skin testing, there is almost a 100 percent chance you are not allergic. It occurs at a rate of about 7 per 1 million vaccinated women between 18 and 49 years old. 2019; doi:10.1001/jama.2018.19283. In rare cases, an allergy to penicillin can cause an anaphylactic reaction, which can be deadly. Therefore, the risk of developing a severe allergic reaction is very low. Home | About | Contact | Copyright | Privacy | Cookie Policy | Terms & Conditions | Sitemap. If you develop flushing or hives within a few hours of taking a medication, call a board-certified allergist. Skin prick testing is usually not painful. Precipitated sulfur (derivative of elemental sulfur) is synonymous with precipitated sulphur. Over the years, 10% of penicillin users have had reports of mild to severe allergic reactions to the medication. However, even with treatment, the signs and symptoms of an allergic reaction to penicillin can last anywhere from 2 to 4 weeks. Headaches. Mile allergic reactions can be controlled well with the help of antihistamine drugs but, anaphylaxis is a medical emergency that needs to be corrected through epinephrine injections. 11. Studies show only about 20 percent of people will be allergic to penicillin 10 years after their initial allergic reaction if they are not exposed to it again during this time period. Tell any new health care provider about your allergy. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. If we combine this information with your protected The test, if positive, will cause local itching and redness with swelling at the site where the test is performed. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter Digital Edition. Penicillin medications include: Amoxicillin Ampicillin Dicloxacillin Penicillin G Penicillin V Nafcillin Piperacillin Oxacillin Ticarcillin Required fields are marked *. gentamicin) and glycopeptides (e.g. Today, the family of penicillin drugs includes more than 15 different antibiotics, such as: Penicillin Ampicillin Amoxicillin Methicillin. However, recent studies reveal most people who believe theyre allergic to penicillin may actually be able to safely use it either because they never were truly allergic or because they lost sensitivity over time. Penicillin is prescribed for treating various bacterial infections. Sulfa drugs kill bacteria and fungi by interfering with cell metabolism. How accurate is blood test for penicillin allergy? Either oral or injected corticosteroids may be used to treat inflammation associated with more-serious reactions. If the test is positive, you may have some local swelling and itching, but this reaction will go away within an hour or so. Doctors most often prescribe penicillin or amoxicillin (Amoxil) to treat strep throat. 2017;17(3):251-5. Amoxicillin rash: When should I be concerned? Not all bacterial infections are treated with penicillin, but if you have an infection that is usually treated by penicillin, you may be able to take a drug that is similar to penicillin called a cephalosporin. What to know when we add a new business or post? Last updated on July 5, 2021. These conditions include: You may experience side effects of penicillin as happens with other medications that are not an allergic reaction to the drug. Accessed Oct. 22, 2019. Merck Manual Professional Version. Select one or more newsletters to continue. Read more: Could I be allergic to water? It's also very likely that you have outgrown an allergy to penicillin, especially if the reaction happened more than 10 years ago. I was told that I was allergic to amoxicillin, do I still need to see an allergist / immunologist? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Click here for an email preview. Alternative antibiotics to penicillin often called broad spectrum may be less effective in treating an infection, may cause unwanted side effects or may be more expensive. These are just a few examples of common drug side effects. Garlic. Can you take hydroxyzine for anxiety and sleep? 8. This article deals with alternative antibiotics to penicillin in case of penicillin allergy. What do they prescribe if you are allergic to penicillin? clarithromycin), aminoglycosides (e.g. The American College of Allergy, Asthma and Immunology lists the following antibiotics as ones to avoid if you have a penicillin allergy: It can be quite a struggle living with penicillin allergy especially if youre prone to illnesses, infections or injuries. Penicillin is recommended for all clinical stages of syphilis, and no proven alternatives exist for treating neurosyphilis, congenital syphilis, or syphilis during pregnancy. Antibodies are formed against the penicillin antibiotics. Allergy to penicillin and alternative antibiotics, See numbered references within the article, Difficulty in breathing and chest tightness, Cold clammy skin or blue discoloration of skin. A total of 36 drugs are known to interact with Penicillin VK . . Salicylate Allergy Symptoms. According to the Centers for Disease Control and Prevention, less than 1 percent of people have a true penicillin allergy, even though about 10 percent of people tell their doctors they are allergic to penicillin. Your doctor will then do an oral challenge. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Among all groups of antibiotics, penicillins are the oldest and the safest ones with fewer side effects. This family contains antibiotics that come from a fungus called Penicillium. Other examples include the antibiotics ampicillin and nafcillin. 2023 Caniry - All Rights Reserved Even if you think you are allergic to penicillin, allergies change over time and it is worth discussing your history with your allergist / immunologist who may suggest testing to help clarify your allergy history. Allegra vs Zyrtec: What's the difference? This largely depends on your history and an allergist / immunologist can help clear this up. Serious allergic reactions to . If you are allergic to one or both of these foods, you should check for their presence in any medications you take. When folic acid synthesis is inhibited, DNA replication will be reduced and bacterial cells will stop dividing. Your email address will not be published. Acad Pediatr. Drugs can also interact with each other, with foods, or with supplements. The decision of whether you need to carry an epinephrine autoinjector should be made after specialty consultation with your allergist / immunologist. Penicillin was discovered in 1828. Tightening of the airways and throat, causing trouble breathing, A history of other allergies, such as food allergy or hay fever, Increased exposure to penicillin, because of high doses, repetitive use or prolonged use, Certain illnesses commonly associated with allergic drug reactions, such as infection with. Mycoplasma hominis infection of the female pelvic organs. Find out more about drug allergies. Can I take amoxicillin if Im allergic to penicillin? doxycycline), quinolones (e.g. As the name is indicating, these enzymes start killing and engulfing the cells causing their autolysis. Had the reaction within one hour of taking penicillin, Developed raised and itchy skin patches (hives), Had swelling of your face, throat, hands or feet (angioedema), Had wheezing, chest tightness or difficulty breathing. Zithromax is not a penicillin it is a type of antibiotic called a macrolide. If you are allergic to penicillin or another antibiotic, you can still receive either of the COVID-19 vaccines. Accessed Oct. 24, 2019. If you are allergic to egg, consult with your doctor before getting a vaccine. The clavulanic acid ingredient makes Augmentin effective against bacteria that amoxicillin or other penicillin drugs may not work against when theyre taken by themselves. That means you will get a dose of penicillin and be observed in the office. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. People can be allergic to certain vaccines. For a true allergy, you should not take any antibiotics in the penicillin family. You may be sent to an allergist for testing. If the tests are negative, the next step is an oral challenge drinking a tiny dose of liquid penicillin to see if you are allergic.. Penicillin allergy is an abnormal reaction of your immune system to the antibiotic drug penicillin. Penicillin allergy is an abnormal reaction of your immune system to the antibiotic drug penicillin. First, the patient undergoes a series of skin prick tests using gradually increasing amounts of penicillin. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Thus, the diagnosis of penicillin allergy cannot be made alone on the basis of signs and symptoms because mild allergic reactions often mimic the side effects of drug. doxycycline), quinolones (e.g. The researchers estimated that both skin tests and blood tests give negative results in more than 95% of individuals who do not have a true penicillin allergy. Once the bacteria lose their cell wall, they begin to die rapidly. Over 95 percent of people with penicillin allergy can safely take cephalosporins, which are a bit structurally different from penicillins. Sustanon is an injectable form of testosterone used as hormone replacement therapy for men with low testosterone. Celecoxib (Celebrex), a nonsteroidal anti-inflammatory drug (NSAID) Sumatriptan (Imitrex, Sumavel Dosepro, Zecuity), a migraine drug Water pills, or diuretics, including furosemide (Lasix) and. Remember that many medicines may look or sound alike, so dont assume a doctor is always able to correctly identify it based on a description. Check out our penicillin allergy infographic. In other cases, a person may report a family history of penicillin allergy, but penicillin allergy is not passed down through families. If certain medications make your skin bloom with hives, cause light-headedness, nausea, difficulty breathing or stomach cramps, or make your throat or mouth swell, it could be the result of a drug allergy. Examples of reactions not involving the immune system include: The impact of a reaction to medication can range from annoying to severe. One study reported in a review in Canadian Family Physician found that penicillin, which is substantially different from sulfa antibiotics, was more likely to cause an allergic reaction than sulfa nonantibiotics among people allergic to sulfa antibiotics. Antibiotics may cause abdominal pain and diarrhea.